| Shoojit | One who is always winning. |
| Shortcake | A sweet, small baked treat. |
| Shota | A big, thick, or stout boy. |
| Shoto | One who flies and soars. |
| Shrav | One who is attentive to all. |
| Shrutikirti | Famous for great wisdom. |
| Shuka | A Sanskrit name meaning parrot. |
| Shuri | A name meaning princess or sun. |
| Shyamolie | A name meaning dark or dusky. |
| Siavan | A name meaning a forest dweller. |
| Siavo | A name meaning a bright spirit. |
| Siddharaja | A name meaning perfect king. |
| Signal | A name meaning a clear sign. |
| Sigridha | A name meaning victory beauty. |
| Sigrisha | A name meaning victory seeker. |
| Sigur | A name meaning victory guard. |
| Sikhandin | One who has a tuft of hair |
| Silicon | A chemical element found in sand |
| Silvermist | A light fog with a silvery hue |
| Simhi | A name meaning a lioness or brave |
| Simhika | A mythological lioness character |
| Sinatra | A surname meaning from Sinagra |
| Sindh | A region near the Indus River |
| Sindhuveer | A brave warrior of the Indus |
| Sintra | A town of hills and royal palaces |
| Siren | A creature of enchanting music |
| Sirocco | A hot Mediterranean wind. |
| Sister | A female sibling by birth. |
| Sit | To rest upon the buttocks. |
| Sitarra | A musical stringed instrument. |
| Six | The number after number five. |
| Skadi | Norse goddess of the winter. |
| Skadiya | A name meaning winter goddess. |
| Skadiyo | A variation of winter goddess. |
| Skuld | One of the three Norse fates. |
| Slash | To cut with a sweeping stroke. |
| Snapdragon | A flower resembling a dragon. |
| Snooki | A nickname meaning small nose. |
| Snoop | To pry or investigate secretly. |
| Sobek | Ancient Egyptian god of the Nile. |